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p300 Polyclonal Antibody

CAT: 0965-JOT-AP06773-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06773-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EP300 (E1A binding protein p300) encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in EP300 are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
CAS Number
9007-83-4
Synonyms
EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
Synthesized peptide derived from the Internal region of human p300.
Clonality
Polyclonal
Applications
IF, WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
264161
Antibody Type
Primary antibody
Isotype
IgG

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