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p300(Phospho Ser89) Polyclonal Antibody

CAT: 0965-JOT-AP12632-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12632-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
CAS Number
9007-83-4
Synonyms
Histone acetyltransferase p300; EP300; P300; Histone acetyltransferase p300; p300 HAT; E1A-associated protein p300
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human p300 around the phosphorylation site of Ser89. AA range:55-104
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
264144
Antibody Type
Primary antibody
Isotype
IgG

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