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NMDAEpsilon3 Polyclonal Antibody

CAT: 0965-JOT-AP06076-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06076-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GRIN2C encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
GRIN2C; NMDAR2C; Glutamate [NMDA] receptor subunit epsilon-3; N-methyl D-aspartate receptor subtype 2C; NMDAR2C; NR2C
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human NMDAepsilon3. AA range:937-986
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
134240
Antibody Type
Primary antibody
Isotype
IgG