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NMDAEpsilon1/2 Polyclonal Antibody

CAT: 0965-JOT-AP06072-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP06072-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GRIN2A encodes a member of the glutamate-gated ion channel protein family. The glutamate ionotropic receptor NMDA type subunit 2A is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
GRIN2A; NMDAR2A; Glutamate [NMDA] receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A; hNR2A; GRIN2B; NMDAR2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-a
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human NMDAR2A/B. AA range:1216-1265
Clonality
Polyclonal
Applications
IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
165283/166367
Antibody Type
Primary antibody
Isotype
IgG

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