NF-YA Polyclonal Antibody

CAT: 0965-JOT-AP05969-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP05969-01Size:20 µL

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Background

The protein encoded by NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in NFYA product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

CAS Number

9007-83-4

Synonyms

NFYA; Nuclear transcription factor Y subunit alpha; CAAT box DNA-binding protein subunit A; Nuclear transcription factor Y subunit A; NF-YA

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human NFYA. AA range:261-310

Clonality

Polyclonal

Applications

WB, IHC-p, IF, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

36877

Antibody Type

Primary antibody

Isotype

IgG

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NF-YA Polyclonal Antibody

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