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NF-L Polyclonal Antibody

CAT: 0965-JOT-AP05964-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP05964-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
CAS Number
9007-83-4
Synonyms
NEFL; NF68; NFL; Neurofilament light polypeptide; NF-L; 68 kDa neurofilament protein; Neurofilament triplet L protein
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human NF-L. AA range:295-344
Clonality
Polyclonal
Applications
IHC-p, WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
61517
Antibody Type
Primary antibody
Isotype
IgG

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