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Insulin R Polyclonal Antibody

CAT: 0965-JOT-AP04564-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04564-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
INSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
INSR; Insulin receptor; IR; CD antigen CD220
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IR. AA range:1331-1380
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
156307
Antibody Type
Primary antibody
Isotype
IgG

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