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GPR31 Polyclonal Antibody

CAT: 0965-JOT-AP03737-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03737-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GPR31 (G Protein-Coupled Receptor 31) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR3. igh-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.
CAS Number
9007-83-4
Synonyms
GPR31; 12-(S)-hydroxy-5; 8,10,14-eicosatetraenoic acid receptor; 12-(S)-HETE receptor; 12-HETER; G-protein coupled receptor 31
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR31. AA range:181-230
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
35075
Antibody Type
Primary antibody
Isotype
IgG

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