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Dexras2 Polyclonal Antibody

CAT: 0965-JOT-AP02572-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02572-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RASD2 belongs to the Ras superfamily of small GTPases and is enriched in the striatum. The RASD family member 2 functions as an E3 ligase for attachment of small ubiquitin-like modifier (SUMO). This protein also binds to mutant huntingtin (mHtt), the protein mutated in Huntington disease (HD). Sumoylation of mHTT by this protein may cause degeneration of the striatum. The protein functions as an activator of mechanistic target of rapamycin 1 (mTOR1), which in turn plays a role in myelination, axon growth and regeneration. Reduced levels of mRNA expressed by this gene were found in HD patients.
CAS Number
9007-83-4
Synonyms
RASD2; TEM2; GTP-binding protein Rhes; Ras homolog enriched in striatum; Tumor endothelial marker 2
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human RASD2. AA range:217-266
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
30366
Antibody Type
Primary antibody
Isotype
IgG

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