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COL9A1 Polyclonal Antibody

CAT: 0965-JOT-AP02097-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02097-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
COL9A1 encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
CAS Number
9007-83-4
Synonyms
COL9A1; Collagen alpha-1(IX) chain
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
Synthesized peptide derived from COL9A1 . at AA range: 390-470
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
91855
Antibody Type
Primary antibody
Isotype
IgG