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COL17A1 Polyclonal Antibody

CAT: 0965-JOT-AP02068-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02068-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
COL17A1 encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.
CAS Number
9007-83-4
Synonyms
COL17A1; BP180; BPAG2; Collagen alpha-1(XVII) chain; 180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
Synthesized peptide derived from COL17A1 . at AA range: 1-80
Clonality
Polyclonal
Applications
IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
150419
Antibody Type
Primary antibody
Isotype
IgG

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