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CD3-Epsilon Polyclonal Antibody

CAT: 0965-JOT-AP01497-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP01497-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by CD3E (CD3e molecule) is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in CD3E cause immunodeficiency. CD3E has also been linked to a susceptibility to type I diabetes in women.
CAS Number
9007-83-4
Synonyms
CD3E; T3E; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain; CD antigen CD3e
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human CD3-epsilon. AA range:22-71
Clonality
Polyclonal
Applications
WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
23147
Antibody Type
Primary antibody
Isotype
IgG

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