PKC Epsilon Polyclonal Antibody

CAT: 0965-JOT-AP07219-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP07219-01Size:20 µL

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Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by PRKCE (protein kinase C epsilon)is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.

CAS Number

9007-83-4

Synonyms

PRKCE; PKCE; Protein kinase C epsilon type; nPKC-epsilon

Host

Rabbit

Reactivity

Human;Mouse;Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human PKC epsilon. AA range:688-737

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

83674

Antibody Type

Primary antibody

Isotype

IgG

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