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Bcl-6 Polyclonal Antibody

CAT: 0965-JOT-AP00864-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00864-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
B-cell lymphoma 6 protein encoded by BCL6 is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
CAS Number
9007-83-4
Synonyms
BCL6; BCL5; LAZ3; ZBTB27; ZNF51; B-cell lymphoma 6 protein; BCL-6; B-cell lymphoma 5 protein; BCL-5; Protein LAZ-3; Zinc finger and BTB domain-containing protein 27; Zinc finger protein 51
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human BCL6. AA range:271-320
Clonality
Polyclonal
Applications
IF, WB, IHC-p, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
78846
Antibody Type
Primary antibody
Isotype
IgG

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