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APC5 Polyclonal Antibody

CAT: 0965-JOT-AP00512-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00512-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ANAPC5 encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein (anaphase promoting complex subunit 5) is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
CAS Number
9007-83-4
Synonyms
ANAPC5; APC5; Anaphase-promoting complex subunit 5; APC5; Cyclosome subunit 5
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
85077
Antibody Type
Primary antibody
Isotype
IgG

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