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APC Polyclonal Antibody

CAT: 0965-JOT-AP00507-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP00507-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
APC encodes a tumor suppressor protein (APC, WNT signaling pathway regulator) that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in APC cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
CAS Number
9007-83-4
Synonyms
APC; DP2.5; Adenomatous polyposis coli protein; Protein APC; Deleted in polyposis 2.5
Host
Rabbit
Reactivity
Human;Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human APC. AA range:2794-2843
Clonality
Polyclonal
Applications
WB, IHC-p, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
311646
Antibody Type
Primary antibody
Isotype
IgG

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