AIRE-1 Polyclonal Antibody

CAT: 0965-JOT-AP00311-01Size: 20 µLDry Ice: NoHazardous: No

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CAT#:0965-JOT-AP00311-01Size:20 µL

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Background

AIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).

CAS Number

9007-83-4

Synonyms

AIRE; APECED; Autoimmune regulator; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; APECED protein

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human AIRE. AA range:126-175

Clonality

Polyclonal

Applications

WB, ELISA

Stability

-20°C for one year

Concentration

1 mg/ml

Molecular Weight

57727

Antibody Type

Primary antibody

Isotype

IgG

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AIRE-1 Polyclonal Antibody

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