W140 (hydrobromide)

• UNSPSC Description:

  W140 hydrobromide is a S1P1 antagonist with the Ki of 2.84 μM, and can enhanceof capillary leakage and restoration of lymphocyte egress[1].

• Target Antigen:

  LPL Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/w140-hydrobromide.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=P(O)(O)CC[C@H](N)C(NC1=CC(CCCCCC)=CC=C1)=O.Br

• Molecular Weight:

  423.28

• References & Citations:

  [1]Sanna MG, et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nat Chem Biol. 2006;2(8):434-441.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1246817-25-3