W140 (hydrobromide)

• Description :

  W140 hydrobromide is a S1P1 antagonist with the Ki of 2.84 μM, and can enhanceof capillary leakage and restoration of lymphocyte egress[1].

• UNSPSC :

  12352005

• Target :

  LPL Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/w140-hydrobromide.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=P(O)(O)CC[C@H](N)C(NC1=CC(CCCCCC)=CC=C1)=O.Br

• Molecular Formula :

  C16H28BrN2O4P

• Molecular Weight :

  423.28

• References & Citations :

  [1]Sanna MG, et al. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nat Chem Biol. 2006;2 (8) :434-441.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1246817-25-3]