RecombinantIL-6, Human

CAT: 0384-BK0109-01Size: 10 µgDry Ice: NoHazardous: No
CAT#:0384-BK0109-01Size:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Interleukin-6 (IL-6, also known as IFN-β2) is a pleiotropic cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism, and cancer progression. IL-6 is secreted by T cells and macrophages to stimulate immune response. IL-6 is responsible for stimulating acute phase protein synthesis, as well as the production of neutrophils in the bone marrow. It supports the growth of B cells and is antagonistic to regulatory T cells.Recombinant human Interleukin-6 (rhIL-6) produced in E.coli is a single non-glycosylated polypeptide chain containing 185 amino acids. A fully biologically active molecule, rhIL-6 has a molecular mass of 20.9 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
CAS Number
9000-83-3
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% by SDS-PAGE analysis.
Bioactivity
ED50 <0.1ng/ml, measured by the dose-dependent stimulation of the proliferation of IL-6 dependent murine 7TD1 cells, corresponding to a specific activity of > 1 x 10ˆ7 units/mg.
Reconstitution
Reconstituted in ddH2O at 100 μg/ml.
Molecular Weight
20.9 kDa, observed by reducing SDS-PAGE.
Storage Conditions
Lyophilized recombinant human Interleukin-6 (rhIL-6) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIL-6 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized after extensive dialysis against 1xPBS.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.
AA Sequence
MPVPPGEDS KDVAAPHRQP LTSSERIDKQ IRYILDGISA LRKETCNKSN MCESSKEALA ENNLNLPKMA EKDGCFQSGF NEETCLVKII TGLLEFEVYL EYLQNRFESS EEQARAVQMS TKVLIQFLQK KAKNLDAITT PDPTTNASLL TKLQAQNQWL QDMTTHLILR SFKEFLQSSL RALRQM

Related Products

CatalogName
BK0252-01RecombinantIL-6, His, Mouse
BK0317-01RecombinantIL-6, Rat (HEK293-expressed)
BK0240-01RecombinantIL-2, Human
BK0100-01RecombinantIL-22, Human
BK0236-01RecombinantIL-18BP, Human
BK0245-01RecombinantIL-4, Human
BK0316-01RecombinantIL-4R, Human
BK0106-01RecombinantIL-5, Human
BK0094-01RecombinantIL-1β, Human
BK0102-01RecombinantIL-3, Human

Alternative Products

CatalogName
BK0109RecombinantIL-6,Human
BK0253RecombinantIL-6,Human(CHO-expressed)
BK0316RecombinantIL-4R,Human
BK0240RecombinantIL-2,Human
BK0259RecombinantIL-9,Human
BK0104RecombinantIL-33,Human
BK0106RecombinantIL-5,Human
BK0098RecombinantIL-21,Human
BK0254RecombinantIL-6R,Human
BK0100RecombinantIL-22,Human

Popular Products