PER2 Recombinant Rabbit mAb

• Background:

  This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

• Structure Composition:

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative:

  FASPS; FASPS1

• Swiss Prot:

  O15055

• Reactivity:

  Human

• Immunogen:

  A synthetic peptide of human PER2

• Conjugation:

  Unconjugated

• Applications:

  WB, ICC/IF, FC

• Purity:

  Affinity Purification

• Modification:

  Unmodification

• Molecular Weight:

  137 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  IgG

• Applications Notes:

  Western blot analysis of extracts from HeLa cells using it at 1:1000.

• Host or Source:

  Rabbit

• CAS Number:

  9000-83-3