PER3 Recombinant Rabbit mAb

• Background :

  This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2014]

• CAS Number :

  9000-83-3

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  GIG13; FASPS3

• Swiss Prot :

  P56645

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human PER3

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB: 1:1000-1:2000

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  132 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot analysis of extracts from T24, C2C12 cells and Rat heart tissue using it at 1:1000.

• Host or Source :

  Rabbit