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SSRP1 Recombinant Rabbit mAb

CAT: 0384-BS45897-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS45897-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008]
CAS Number
9000-83-3
Structure Composition
Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
Product Name Alternative
FACT; T160; FACT80
Swiss Prot
Q08945
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide of human SSRP1
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:1000-1:5000
Purity
Affinity Purification
Modification
Unmodification
Molecular Weight
81 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
IgG
Applications Notes
Western blot analysis of extracts from K562, 293T cells using it at 1:1000.
Host or Source
Rabbit

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