YTHDC2 Recombinant Rabbit mAb

• Background :

  This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  CAHL; hYTHDC2

• Swiss Prot :

  B2RR83

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant protein of human YTHDC2

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, FC, IP

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  160 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot detection of YTHDC2 in Hela, A549, HL-60, U251, U87-MG cell lysates using YTHDC2 antibody (1:1000 diluted) .

• Host or Source :

  Rabbit

• CAS Number :

  9000-83-3