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SAV1 polyclonal antibody

CAT: 0384-BS71396-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS71396-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
SAV1; SAV; WW45; WWP4
Swiss Prot
Q9H4B6
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human SAV1 (NP_068590.1) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:1000 - 1:4000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
45kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit

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