GPM6A polyclonal antibody

• Background :

  Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK and Src signaling pathways. May be involved in neuronal NGF-dependent Ca (2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs; enhances internalization and recycling of mu-type opioid receptor.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  GPM6A; GPM6; M6A

• Swiss Prot :

  P51674

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthetic peptide of human GPM6A (NP_005268.1) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC

• Dilution :

  WB,1:500 - 1:2000|IHC,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  31kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Polyclonal Antibodies

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4