RNF34 polyclonal antibody

• Background :

  The protein encoded by this gene contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms.

• Structure Composition :

  1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative :

  RNF34; CARP-1; CARP1; RFI; RIF; RIFF; hRFI

• Swiss Prot :

  Q969K3

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human RNF34 (NP_079402.2) .

• Conjugation :

  Unconjugated

• Applications :

  WB, IF/ICC

• Dilution :

  WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200

• Purity :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification :

  Unmodification

• Molecular Weight :

  42kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Polyclonal Antibodies

• Host or Source :

  Rabbit

• CAS Number :

  9007-83-4