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TGS1 polyclonal antibody

CAT: 0384-BS70955-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS70955-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m (7G caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m (2,2,7G cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs. Plays a role in transcriptional regulation.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
TGS1; NCOA6IP; PIMT; PIPMT
Swiss Prot
Q96RS0
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein of human TGS1 (NP_079107.6) .
Conjugation
Unconjugated
Applications
WB
Dilution
WB,1:500 - 1:2000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
97kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit

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