CSRNP1 polyclonal antibody
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CSRNP1 polyclonal antibody
Background:
This gene encodes a protein that localizes to the nucleus and expression of this gene is induced in response to elevated levels of axin. The Wnt signalling pathway, which is negatively regulated by axin, is important in axis formation in early development and impaired regulation of this signalling pathway is often involved in tumors. A decreased level of expression of this gene in tumors compared to the level of expression in their corresponding normal tissues suggests that this gene product has a tumor suppressor function. Alternative splicing results in multiple transcript variants.Structure Composition:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2Product Name Alternative:
CSRNP1; AXUD1; CSRNP-1; FAM130B; TAIP-3; URAX1Swiss Prot:
Q96S65Reactivity:
Human, Mouse, RatImmunogen:
Recombinant fusion protein of human CSRNP1 (NP_149016.2) .Conjugation:
UnconjugatedApplications:
WB, IHC, IF/ICCDilution:
WB,1:500 - 1:2000|IHC,1:50 - 1:200|IF/ICC,1:50 - 1:100Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .Modification:
UnmodificationMolecular Weight:
Refer to figuresStorage Conditions:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.Notes:
For research use only, not for use in diagnostic procedure.Specificity:
Polyclonal AntibodiesApplications Notes:
Immunohistochemistry of paraffin-embedded rat kidney using CSRNP1 antibody at dilution of 1:200 .Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.Host or Source:
RabbitCAS Number:
9007-83-4
