Products for Research Use Only
RegisterLogin

PXR polyclonal antibody

CAT: 0384-BS7284-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS7284-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.
CAS Number
9007-83-4
Structure Composition
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NR1I2; BXR; ONR1; PAR; PAR1; PAR2; PARq; PRR; PXR; SAR; SXR
Swiss Prot
O75469
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human PXR (NP_003880.3) .
Conjugation
Unconjugated
Applications
WB, IF/ICC, IP
Dilution
WB,1:500 - 1:2000|IF/ICC,1:50 - 1:200|IP,1:50 - 1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
50KDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Polyclonal Antibodies
Host or Source
Rabbit

Related Products

CatalogName
PPL50078-4aPLVX-Puro-Flag-PXR
BZ16794-01Polyclonal antibodyPN1 polyclonal antibody
BS75206-01AaaaaASPH polyclonal antibody
BS65563-01Mras polyclonal antibody
BS7930-01TRPM2 polyclonal antibody
BS8744-01TPH2 polyclonal antibody
BS62356-01CSP polyclonal antibody
BS90079ApoER2 polyclonal antibody
BS8248-01NGB polyclonal antibody
BS91398UBC9 polyclonal antibody

Alternative Products

CatalogName
APR00460GPolyclonal Spt16 polyclonal antibody
APG01659GPolyclonal AKR1B10 Polyclonal Antibody
APR11188GPolyclonal Rtf1 polyclonal antibody
AMR09486GPolyclonal PPARG polyclonal antibody
APR13475GPolyclonal SOX4 polyclonal antibody
APR00375GPolyclonal JMJD2c polyclonal antibody
APR00449GPolyclonal Hira polyclonal antibody
APR12525GPolyclonal MeCP2 polyclonal antibody
APR00376GPolyclonal BMI1 polyclonal antibody
APR00459GPolyclonal CHD4 polyclonal antibody

Popular Products