SETBP1 polyclonal antibody

• Background:

  This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  SET-binding protein; SEB; SETBP1; KIAA0437

• Swiss Prot:

  Q9Y6X0

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant full length Human SETBP1.

• Conjugation:

  Unconjugated

• Applications:

  WB IF

• Dilution:

  WB: 1:500~1:2000 IF: 1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 175kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  SETBP1 polyclonal antibody detects endogenous levels of SETBP1 protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using SETBP1 antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4