CRY1 polyclonal antibody

CAT: 0384-BS8561-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS8561-01Size:50 µL
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Background
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cryptochrome-1; CRY1; PHLL1
Swiss Prot
Q16526
Reactivity
Human, Mouse
Immunogen
Recombinant full length Human CRY1.
Conjugation
Unconjugated
Applications
WB IHC
Dilution
WB: 1:500~1:2000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 66kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CRY1 polyclonal antibody detects endogenous levels of CRY1 protein.
Applications Notes
Western blot analysis of extracts of NCI-H460 cell lines, using CRY1 antibody.
Host or Source
Rabbit

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