DTYMK polyclonal antibody

• Background:

  DTYMK (deoxythymidylate kinase (thymidylate kinase) ), also known as CDC8, TMPK, TYMK or dTMP kinase, is a 212 amino acid protein that belongs to the thymidylate kinase family and is involved in pyrimidine metabolism. Specifically, DTYMK catalyzes the ATP-dependent conversion of dTMP (deoxythymidine monophosphate) to dTDP (deoxythymidine diphosphate), which then functions as one of the four nucleotides in DNA. Via its role in the catalytic creation of dTDP, DTYMK plays an important role in the pathway of DNA synthesis and is thought to be involved in cell cycle progression and cell growth. DTYMK expression levels peak during the S phase (synthesis phase) of the cell cycle, further supporting the role of DTYMK in DNA synthesis.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Thymidylate kinase; dTMP kinase; DTYMK; CDC8; TMPK; TYMK

• Swiss Prot:

  P23919

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length Human DTYMK.

• Conjugation:

  Unconjugated

• Applications:

  WB IF

• Dilution:

  WB 1:500 - 1:2000 IF 1:50 - 1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 23kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  DTYMK polyclonal antibody detects endogenous levels of DTYMK protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using DTYMK antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4