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BCL2L14 polyclonal antibody

CAT: 0384-BS8249-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS8249-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. Bcl-2 is one of many key regulators of apoptosis that are essential for proper development, tissue homeostasis and protection against foreign pathogens. Bcl-G, also known as BCL2L14 (BCL2-like 14) or BCLG, is a 327 amino acid cytoplasmic protein that belongs to the Bcl-2 family of apoptosis-regulating proteins. Bcl-G is expressed as three alternatively spliced transcripts designated short, medium and long. The short isoform is testis-specific and localizes to cytosolic organelles, while the long isoform is widely expressed and is distributed throughout the cytosol. Overexpression of Bcl-G induces apoptosis in cells, suggesting a possible role for Bcl-G in tumor suppression.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Apoptosis facilitator Bcl-2-like protein 14; Bcl2-L-14; Apoptosis regulator Bcl-G; BCL2L14; BCLG
Swiss Prot
Q9BZR8
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human BCL2L14.
Conjugation
Unconjugated
Applications
WB IF
Dilution
WB: 1:500~1:2000 IF: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 37 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BCL2L14 polyclonal antibody detects endogenous levels of BCL2L14 protein.
Applications Notes
WesternBlot (WB) analysis of BCL2L14 polyclonal antibody
Host or Source
Rabbit

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