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BCL2L12 polyclonal antibody

CAT: 0384-BS67646-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS67646-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2) . The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
CAS Number
9007-83-4
Structure Composition
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Product Name Alternative
BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein
Swiss Prot
Q9HB09
Reactivity
Human
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L12. The exact sequence is proprietary.
Conjugation
Unconjugated
Applications
WB
Dilution
WB (1/500 - 1/1000)
Purity
The antibody was purified by immunogen affinity chromatography.
Modification
Unmodification
Molecular Weight
~ 36 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
Recognizes endogenous levels of BCL2L12 protein.
Applications Notes
Western blot analysis of BCL2L12 expression in K562 (A), HEK293T (B) whole cell lysates.
Host or Source
Rabbit

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