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BLMH polyclonal antibody

CAT: 0384-BS6469-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS6469-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BLM hydrolase (Bleomycin hydrolase, BLM hydrolase, BMH) is a 455 amino acid protein encoded by the human gene BLMH. BLM hydrolase belongs to the cysteine protease papain superfamily and the peptidase C1 family. It is a cytoplasmic cysteine peptidase commonly found as a homohexamer. It is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM) . BLM is an essential component of combination chemotherapy regimens for cancer.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Bleomycin hydrolase; BH; BLM hydrolase; BMH; BLMH
Swiss Prot
Q13867
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant full length Human BLMH.
Conjugation
Unconjugated
Applications
WB IHC IF
Dilution
WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:50
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 53 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
BLMH polyclonal antibody detects endogenous levels of BLMH protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using BLMH antibody.
Host or Source
Rabbit

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