BLMH polyclonal antibody

• Background:

  BLM hydrolase (Bleomycin hydrolase, BLM hydrolase, BMH) is a 455 amino acid protein encoded by the human gene BLMH. BLM hydrolase belongs to the cysteine protease papain superfamily and the peptidase C1 family. It is a cytoplasmic cysteine peptidase commonly found as a homohexamer. It is highly conserved through evolution, however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM) . BLM is an essential component of combination chemotherapy regimens for cancer.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Bleomycin hydrolase; BH; BLM hydrolase; BMH; BLMH

• Swiss Prot:

  Q13867

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant full length Human BLMH.

• Conjugation:

  Unconjugated

• Applications:

  WB IHC IF

• Dilution:

  WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:20 - 1:50

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 53 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  BLMH polyclonal antibody detects endogenous levels of BLMH protein.

• Applications Notes:

  Western blot analysis of extracts of various cell lines, using BLMH antibody.

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4