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PNN polyclonal antibody

CAT: 0384-BS61679-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61679-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a MOCA-type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Pinin; 140 kDa nuclear and cell adhesion-related phosphoprotein; Desmosome-associated protein; Domain-rich serine protein; DRS protein; DRSP; Melanoma metastasis clone A protein; Nuclear protein SDK3; SR-like protein; PNN; DRS; MEMA
Swiss Prot
Q9H307
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding Human PNN.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 140 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
PNN polyclonal antibody detects endogenous levels of PNN protein.
Applications Notes
Western blot (WB) analysis of PNN polyclonal antibody at 1:500 dilution Lane1:C6 whole cell lysate (40ug) Lane2:PC12 whole cell lysate (40ug) Lane3:CT26 whole cell lysate (40ug) Lane4:HCT116 whole cell lysate (40ug) Lane5:HepG2 whole cell lysate (40ug)
Host or Source
Rabbit

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