KANK2 polyclonal antibody

CAT: 0384-BS61445-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS61445-01Size:50 µL
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Background
Involved in transcription regulation by sequestering nuclear receptor coactivators, such as NCOA1, NCOA2 and NCOA3, in the cytoplasm; the function is deregulated by phosphorylation. Involved in the negative control of vitamin D receptor signaling pathway (PubMed:24671081) . May be involved in the control of cytoskeleton formation by regulating actin polymerization. Involved in regulation of caspase-independent apoptosis; proposed to sequester AIFM1 in mitochondria and apoptotic stimuli lead to its proteasomal degradation allowing the release of AIFM1 to the nucleus (PubMed:22371500) . May be involved in promotion of cell proliferation (By similarity) .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
KN motif and ankyrin repeat domain-containing protein 2; Ankyrin repeat domain-containing protein 25; Matrix-remodeling-associated protein 3; SRC-1-interacting protein; SIP; SRC-interacting protein; SRC1-interacting protein; KANK2; ANKRD25; KIAA1518; MXRA3; SIP
Swiss Prot
Q63ZY3
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 340-385 of Human KANK2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 117 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
KANK2 polyclonal antibody detects endogenous levels of KANK2 protein.
Applications Notes
Western blot (WB) analysis of KANK2 polyclonal antibody at 1:1000 dilution Lane1:HELA whole cell lysate (51.3μg) Lane2:The Uterus tissue lysate of Rat (43.4μg) Lane3:The Uterus tissue lysate of Mouse (37.4μg) Lane4:The Heart tissue lysate of Rat (43.4μg) Lane5:The Heart tissue lysate of Mouse (37.4μg)
Host or Source
Rabbit

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