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TSHZ2 polyclonal antibody

CAT: 0384-BS61409-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS61409-01Size:50 µL
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Background
The homeobox DNA-binding domain is a 60 amino acid motif that is conserved among many species and functions to bind DNA via a helix-turn-helix structure, thereby playing a role in transcriptional regulation and the control of gene expression. TSHZ2 (Teashirt homolog 2), also known as ZNF218 (Zinc finger protein 218) and OVC10-2 (Ovarian cancer-related protein 10-2), is a 1034 amino acid nuclear protein that contains one homeobox DNA-binding domain, as well as five C2H2-type zinc fingers. In drosophilia, teashirt genes function as region-specific homeotic genes that specify trunk identity during embryogenesis and these genes seem to conserve the same function in mice. The gene encoding TSHZ2 maps to human chromosome 20, which comprises approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Teashirt homolog 2; Ovarian cancer-related protein 10-2; OVC10-2; Zinc finger protein 218; TSHZ2; C20orf17; TSH2; ZNF218
Swiss Prot
Q9NRE2
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 818-863 of Human TSHZ2.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 115 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TSHZ2 polyclonal antibody detects endogenous levels of TSHZ2 protein.
Applications Notes
Western blot (WB) analysis of TSHZ2 polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate (40ug) Lane2:The Heart tissue lysate of Rat (30ug) Lane3:The Heart tissue lysate of Mouse (30ug)
Host or Source
Rabbit