DFFB polyclonal antibody

CAT: 0384-BS60830-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60830-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The Ced/ICE or caspase family of cysteine proteases plays a pivotol role in mediating apoptosis through the proteolysis of specific targets. Among the targets are poly (ADP-ribose) polymerase (PARP), Gelsolin, ICAD (inhibitor of CAD, also designated DFF-45) and the nuclear lamins. CAD (caspase-activated deoxyribonuclease), also designated CPAN (caspase-activated nuclease) and DFF40, is a DNase that is responsible for DNA degradation during apoptosis. Caspase-3 acts to dissociate CAD from ICAD, allowing CAD to enter the nucleus and degrade DNA.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
DNA fragmentation factor subunit beta (EC:3.-.-.-) ; Caspase-activated deoxyribonuclease; CAD; Caspase-activated DNase; CPAN; DNA fragmentation factor 40 kDa subunit; DFF-40; DFFB
Swiss Prot
O76075
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human DFFB.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 39 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
DFFB polyclonal antibody detects endogenous levels of DFFB protein.
Applications Notes
Western blot (WB) analysis of DFFB polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:MCF-7 whole cell lysate Lane3:H9C2 whole cell lysate Lane4:Raw264.7 whole cell lysate
Host or Source
Rabbit

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