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NLGN3 polyclonal antibody

CAT: 0384-BS60735-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60735-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Neuroligins are a family of plasma membrane proteins that possess an N-terminal hydrophobic domain, a large esterase homology domain, a single transmembrane region, a short cytoplasmic domain, and an EF-hand binding domain . Members of the neuroligin family include Neuroligin 1, Neuroligin 2 and Neuroligin 3 . Neuroligins are expressed in excitatory neuronal synaptic clefts . Neuroligins play a role in the formation and remodeling of CNS synapses by binding to b-neurexins, a family of neuronal cell surface proteins . Neuroexin 1∫ binds to the EF-hand domain of Neuroligin 1 and requires calcium ion . Neuroligins also bind to PSD-95, which may recruit ion channels and neurotransmitter receptors to the synapses .
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Neuroligin-3; Gliotactin homolog; NLGN3; KIAA1480; NL3
Swiss Prot
Q9NZ94
Reactivity
Human, Mouse
Immunogen
A synthetic peptide corresponding to residues in Human NLGN3
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 94 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
NLGN3 polyclonal antibody detects endogenous levels of NLGN3 protein.
Applications Notes
Western blot (WB) analysis of NLGN3 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:sp2/0 whole cell lysate
Host or Source
Rabbit

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