SCD polyclonal antibody

CAT: 0384-BS60618-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS60618-01Size:50 µL
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Background
Stearoyl-CoA desaturase (SCD) is a microsomal enzyme required for the synthesis of oleate and palmitoleate, which are the major monounsaturated fatty acids of membrane phospholipids, triglycerides and cholesterol esters. SCD plays a major role in the triacylglycerol and phospholipid secretion process and in mechanisms of cellular cholesterol homeostasis. It is subject to rapid turnover in the cell and, as such, represents a model for studying selective degradation of short-lived proteins of the ER. SCD is also an important regulator of membrane fluidity. An increase in expression levels of SCD is observed in cells which are induced to differentiate into adipocytes and in certain tumor cell lines. Due to gene duplication events, the number of genes in the SCD family differs between species. Their expression patterns are affected by the level of unsaturated fatty acids in the diet of the animal.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Acyl-CoA desaturase; Delta (9) -desaturase; Delta-9 desaturase; Fatty acid desaturase; Stearoyl-CoA desaturase; SCD
Swiss Prot
O00767
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human SCD
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 42 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SCD polyclonal antibody detects endogenous levels of SCD protein.
Applications Notes
Western blot (WB) analysis of SCD polyclonal antibody at 1:500 dilution Lane1:Hela whole cell lysate Lane2:sp2/0 whole cell lysate Lane3:PC12 whole cell lysate
Host or Source
Rabbit

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