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CFC1B/CFC1 polyclonal antibody

CAT: 0384-BS60336-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60336-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cryptic is a 224 amino acid member of the epidermal growth factor-Cripto-1/ FRL1/cryptic family that consists of extracellular and cell-associated proteins which function as co-receptors for the transforming growth factor b subfamily of proteins. Cryptic is involved in the appropriate establishment of the left-right axis of the organism, and it may play a role in the development of mesoderm and/or neural patterning during gastrulation. Loss-of-function mutations in CFC1, the gene encoding for Cryptic, are associated with human left-right laterality defects. Defects in CFC1 also cause visceral heterotaxy (HTX2), an autosomal disease characterized by a variable group of congenital anomalies that include complex cardiac malformations such as conotruncal heart malformations that may lead to cardiac outflow tract defects, pulmonary atresia, double-outlet right ventricle, truncus arteriosus communis and aortic arch anomalies.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Cryptic family protein 1B; CFC1B
Swiss Prot
P0CG36/P0CG37
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human CFC1B/CFC1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CFC1B/CFC1 polyclonal antibody detects endogenous levels of CFC1B/CFC1 protein.
Applications Notes
Western blot (WB) analysis of CFC1B/CFC1 polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit

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