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LZTR1 polyclonal antibody

CAT: 0384-BS60279-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60279-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LZTR1, leucine-zipper-like transcriptional regulator 1, is a member of the BTBkelch superfamily. LZTR1 contains 2 BTB (POZ) domains and 6 Kelch repeats. The BTB (broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (POxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2 H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. LZTR1 is believed to function as a transcriptional regulator during embryogenesis. LZTR1 is expressed in fetal brain, heart, kidney, liver and lung and is found exclusively on the cytoplasmic surface of the Golgi network. LZTR1 likely contributes to the etiology of velocardiofacial/DiGeorge syndrome, as the LZTR1 gene lies within a chromosomal deletion region associated with the disease.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Leucine-zipper-like transcriptional regulator 1; LZTR-1; TCFL2
Swiss Prot
Q8N653
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human LZTR1.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 95 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
LZTR1 polyclonal antibody detects endogenous levels of LZTR1 protein.
Applications Notes
Western blot (WB) analysis of LZTR1 polyclonal antibody at 1:500 dilution Lane1:MCF-7 cell lysate Lane2:Raw264.7 cell lysate Lane3:PC12 cell lysate
Host or Source
Rabbit

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