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RHOQ polyclonal antibody

CAT: 0384-BS60235-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS60235-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Tc10 is a small GTP-binding protein that is induced during nerve injury, where it cooperates with other Rho family members to facilitate nerve regeneration and, in particular, neurite elongation. tc10 is located predominantly in the plasma membrane, a property that depends both on its post-translational prenylation and on its ability to bind and hydrolyze GTP. tc10 colocalizes to actin filaments and interacts with the actin-binding and filament-forming protein, profilin. tc10 functions to regulate cellular signaling to the actin cytoskeleton and processes associated with cell growth. tc10 also interacts with a similar subset of effectors for Cdc42 and is regulated differentially by p50Rho GTPase-activating protein. Activated tc10 interacts with a variety of putative Rho family effectors, stimulates JNK, and induces filopodial formation.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Rho-related GTP-binding protein RhoQ ; Ras-like protein TC10; Ras-like protein family member 7A; RHOQ; ARHQ; RASL7A; TC10
Swiss Prot
P17081
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to residues in Human RHOQ.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 20 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
RHOQ polyclonal antibody detects endogenous levels of RHOQ protein.
Applications Notes
Western blot (WB) analysis of RHOQ polyclonal antibody at 1:500 dilution Lane1:HEK293T whole cell lysate Lane2:Raw264.7 whole cell lysate Lane3:H9C2 whole cell lysate
Host or Source
Rabbit

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