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RHOQ Polyclonal Antibody

CAT: 0749-ABP60171-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60171-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RHOQ (Ras Homolog Family Member Q) encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
Description
Rabbit Anti-RHOQ Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Rho-related GTP-binding protein RhoQ; Ras-like protein TC10; Ras-like protein family member 7A
Gene ID
23433
Accession Number
P17081
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human RHOQ protein at amino acid sequence of 60-140
Clonality
Polyclonal
Tag
RHOQ
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
22kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RHOQ protein
Observed Molecular Weight
22
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Rho-related GTP-binding protein RhoQ; Ras-like protein TC10; Ras-like protein family member 7A
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P17081
Isotype
Rabbit IgG

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