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MaxiKβ (K119) polyclonal antibody

CAT: 0384-BS3554-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3554-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MaxiK channels are large conductance voltage and Ca 2+-activated potassium channels which are formed by tetramers of MaxiKα subunits, which create pores that are used for smooth muscle tone and neuronal excitability. These MaxiKα subunits have the ability to coassemble with MaxiKβ subunits that are structurally related and are able to regulate the function of MaxiKα subunits. KCNMB4 (potassium large conductance calcium-activated channel, subfamily M, β member 4), also known as Slo-β-4 or Maxi K channel subunit β-4, is a 210 amino acid multi-pass membrane protein belonging to the KCNMB family. Predominantly expressed in brain, KCNMB4 is a regulatory subunit of the calcium activated potassium MaxiKα channel. KCNMB4 contributes to MaxiKα channel diversity by modulating calcium sensitivity and gating kinetics of MaxiKα.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
Calcium-activated potassium channel subunit beta-4; BK channel subunit beta-4; BKbeta4; Hbeta4; Calcium-activated potassium channel; subfamily M subunit beta-4; Charybdotoxin receptor subunit beta-4; K (VCA) beta-4; Maxi K channel subunit beta-4; Slo-beta-4; KCNMB4
Swiss Prot
Q86W47
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 86-140 of Human MaxiKβ.
Conjugation
Unconjugated
Applications
IHC
Dilution
IHC:1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 24 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MaxiKβ (K119) polyclonal antibody detects endogenous levels of MaxiKβ protein.
Host or Source
Rabbit

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