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TRAF3 (S289) polyclonal antibody

CAT: 0384-BS3466-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS3466-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
TRAF1 and TRAF2 (for TNF receptor-associated factors 1 and 2, respectively) . Both function to form heterodimeric complexes and associate with the cytoplasmic domain of TNF-R2. A third member of this protein family, alternatively designated CD40 bp, CRAF1, LAP1 or TRAF3, has been identified and shown to associate with the cytoplasmic domain of CD40. The similarity between a specific region of TRAF3 with regions of TRAF1 and TRAF2 define a “TRAF-C” domain that is necessary and sufficient for CD40 binding and homodimerization.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
CD40 receptor-associated factor 1; CRAF1; CD40-binding protein; CD40BP; LMP1-associated protein; LAP1; CAP-1; TRAF3; 7187; TRAF3; 601896; Q13114; CAP-1; CD40bp; CRAF1; LAP1
Swiss Prot
Q13114
Reactivity
Human
Immunogen
Synthetic peptide, corresponding to amino acids 250-300 of Human TRAF3.
Conjugation
Unconjugated
Related Pathways
NF-kB Signaling, STING Signaling, Toll-like Receptor signaling, Death Receptor Signaling
Applications
WB
Dilution
WB: 1:500~1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 68 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
TRAF3 (S289) polyclonal antibody detects endogenous levels of TRAF3 protein.
Applications Notes
Western blot (WB) analysis of TRAF3 (S289) pAb at 1:500 dilution Lane1:HEK293T whole cell lysate (40ug) Lane2:HCT116 whole cell lysate (20ug) Lane3:A549 whole cell lysate (40ug) Lane4:U-87MG whole cell lysate (40ug)
Host or Source
Rabbit

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