Products for Research Use Only
RegisterLogin

MAPKAPK-2 (S328) polyclonal antibody

CAT: 0384-BS1808-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BS1808-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
MAPKAP Kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAPK-2; MK2; EC 2.7.11.1; MAPKAPK2
Swiss Prot
P49137
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide, corresponding to amino acids 300-350 of Human MAPKAPK-2.
Conjugation
Unconjugated
Related Pathways
Regulation of Microtubule Dynamics, Signaling Pathways Activating p38 MAP KinaseMAPK Erk in Growth and Differentiation Pathway
Applications
WB IHC
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 46 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
MAPKAPK-2 (S328) polyclonal antibody detects endogenous levels of MAPKAPK-2 protein.
Applications Notes
Western blot (WB) analysis of MAPKAPK-2 (S328) polyclonal antibody at 1:500 dilution Lane1:C6 whole cell lysate (40ug) Lane2:The Brain tissue lysate of Rat (40ug) Lane3:The Brain tissue lysate of Mouse (40ug) Lane4:HEK293T whole cell lysate (40ug)
Host or Source
Rabbit

Related Products

CatalogName
AP0573-01MAPKAPK-2 (T334) polyclonal antibody
BS3766MAPKAPK-2 (N266) polyclonal antibody
BS3720MAPKAPK-2 (N218) polyclonal antibody
AP0509-01MAPKAPK-2 (Phospho-T334) polyclonal antibody
BS65376-01MAPKAPK-2 (phospho Ser272) Polyclonal Antibody
BS4902-01MAPKAPK-2 (phospho-S272) polyclonal antibody
BS64056-01P47-phox (phospho-S328) polyclonal antibody
BS74143-01Phospho-MAPKAPK-2/MK2-T334 polyclonal antibody
BS74160-01Phospho-MAPKAPK-2/MK2-T334 polyclonal antibody
BS90823MAPKAP Kinase 2 polyclonal antibody

Alternative Products

CatalogName
GTR18041544-01MAPKAPK-2 (S328) polyclonal antibody
A01193S328Anti-MAPKAPK-2 (S328) Antibody
JOT-AP05212-01MAPKAPK-2 Polyclonal Antibody
APR00023GPolyclonal MAPKAPK-2 Antibody
GTR18043324-01MAPKAPK-2 (N218) polyclonal antibody
GTR18042563-01MAPKAPK-2 (N266) polyclonal antibody

Popular Products