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ND3 polyclonal antibody

CAT: 0384-BS1406-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS1406-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NADH:ubiquinone oxidoreductase (complex I) is an extremely complicated multiprotein complex located in the inner mitochondrial membrane. Human complex I is important for energy metabolism because its main function is to transport electrons from NADH to ubiquinone, which is accompanied by trans-location of protons from the mitochondrial matrix to the intermembrane space. Human complex I appears to consist of 41 subunits. A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the cytoplasm. NADH dehydrogenase subunit 3 (ND3) localizes to the hydrophobic protein fragment of complex I. Mutations in the gene encodiing for ND3 may be associated with Parkinson disease.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
NADH-ubiquinone oxidoreductase chain 3 (EC:1.6.5.3) ; NADH dehydrogenase subunit 3; Mtnd3; mt-Nd3; Nd3
Swiss Prot
P03899
Reactivity
Mouse
Immunogen
A synthetic peptide corresponding to amino acids 21-34 of Mouse ND3.
Conjugation
Unconjugated
Applications
WB
Dilution
WB: 1:500~1:1000 IHC: 1:50~1:200
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
~ 13 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
ND3 polyclonal antibody detects endogenous levels of ND3 protein.
Applications Notes
Western blot (WB) analysis of ND3 polyclonal antibody at 1:1000 dilution Lane1:The muscle tissue lysate of Mouse (47μg)
Host or Source
Rabbit

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