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APOBEC3B polyclonal antibody

CAT: 0384-BS71688-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS71688-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2012]
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Product Name Alternative
DNA dC->dU-editing enzyme APOBEC-3B; A3B; Phorbolin-1-related protein; Phorbolin-2/3
Swiss Prot
Q9UH17
Reactivity
Human
Immunogen
Recombinant protein of human APOBEC3B
Conjugation
Unconjugated
Applications
WB
Dilution
WB 1:200 - 1:1000
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodification
Molecular Weight
46 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
APOBEC3B polyclonal antibody detects endogenous levels of APOBEC3B protein.
Applications Notes
Western blot analysis of extracts of various cell lines, using APOBEC3B antibody.
Host or Source
Rabbit

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